Based on the graphic novel series of the same name Priest is a futuristic horror sci fi based in an alternate reality that combines religion and vampires (arguably a match made in heaven if you will pardon the pun).
A raging war between humans and vampires is drawing to a close, the church has appointed warrior priests with fighting skills to destroy the remaining vampires or intern them in reservations far from the chaotic cities ruled by their order. When the war is over, the church; afraid of the priest’s power, strip them of their title and they are outcast.
After many years of peace the priests are soon forgotten that is of course, until word gets out that one of the priest’s brother and family living in an outpost of the city have been attacked by vampires and his niece taken by them. After asking the permission and being denied by the church to go after them, the priest breaks his vows and goes anyway. What he discovers may well bring about the end of the human race.
Priest suffers from the same issue I had with Cowboys and Aliens, only in this instance it is the premise that sounds cooler than the outcome.... shame really.